PXD023412

PXD023412 is an original dataset announced via ProteomeXchange.

Title	Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons
Description	The transfection of the in vitro neurons was conducted using the lentivirus for under-expression (partial silencing) or over-expression of RAB3GAP1 to separate UE-RAB3GAP1 (RAB3GAP1 under-expression), UE-Ctrl (over-expression control), OE-RAB3GAP1 (RAB3GAP1 over-expression), and OE-Ctrl (under-expression control) groups. Differential proteomes were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrometry.
HostingRepository	iProX
AnnounceDate	2021-01-04
AnnouncementXML	Submission_2022-09-19_01:16:19.000.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jian Zhou
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	iTRAQ8plex reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-04 19:33:07	ID requested
1	2021-01-04 20:12:49	announced
⏵ 2	2022-09-19 01:16:19	announced	2021-11-02: Update publication information.

Liu Y, Tian F, Li S, Chen W, Gong W, Xie H, Liu D, Huang R, Liao W, Yi F, Zhou J, Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons. Amino Acids, 53(9):1339-1350(2021) [pubmed]

submitter keyword: RAB3GAP1, cortical neuron, iTRAQ, PRM, quantitative proteomics

Jian Zhou
contact affiliation	Chongqing Medical university
contact email	zhoujian@cqmu.edu.cn
lab head
Jian Zhou
contact affiliation	Chongqing Medical university
contact email	zhoujian@cqmu.edu.cn
dataset submitter

iProX dataset URI