PXD023378

PXD023378 is an original dataset announced via ProteomeXchange.

Title	A proteomic view of WT and △YdiU Salmonella Typhimurium under iron deficiency condition
Description	Transition metal iron is essential for bacterial survival and growth. For pathogenic bacteria, this challenge is even more severe since human and other mammals have evolved a complicated mechanism of nutritional immunity to restrict iron availability. Preliminary research findings that iron deficiency significantly elevate expression of YdiU. After the ydiU gene was knocked out, the survival ability of Salmonella in iron deficiency medium was significantly reduced. These results suggest that YdiU may act in the survival of Salmonella under iron deficiency stress conditions. Here, we performed a TMT-based comparative quantitative proteomics analysis to reveal the proteomic differences between the WT and △YdiU in iron deficiency.
HostingRepository	PRIDE
AnnounceDate	2022-04-27
AnnouncementXML	Submission_2022-04-27_05:58:37.429.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haihong Jia
SpeciesList	scientific name: Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S; NCBI TaxID: 588858;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-04 03:10:37	ID requested
⏵ 1	2022-04-27 05:58:37	announced

Dataset with its publication pending

submitter keyword: differential protein expression

iron deficiency

WT and △YdiU

Bing qing
contact affiliation	Key Laboratory of Rare and Uncommon Diseases, Department of Microbiology, Institute of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences
contact email	bingqingsdu@163.com
lab head
Haihong Jia
contact affiliation	Key Laboratory of Rare and Uncommon Diseases, Department of Microbiology, Institute of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences
contact email	jia11112222@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD023378

PRIDE project URI

• PRIDE
  1. PXD023378
     1. Label: PRIDE project
     2. Name: A proteomic view of WT and △YdiU Salmonella Typhimurium under iron deficiency condition