PXD023328
PXD023328 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | CD34 is a drug target for AML and CML |
| Description | EGFR inhibitors selectively kill CD34+ leukemia cells and induced clinical remission in patients with high percentage of CD34+ blast |
| HostingRepository | iProX |
| AnnounceDate | 2020-12-30 |
| AnnouncementXML | Submission_2024-02-29_18:16:37.000.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Li Xia |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2020-12-30 19:23:02 | ID requested | |
| 1 | 2023-11-27 18:02:58 | announced | |
| ⏵ 2 | 2024-02-29 18:16:38 | announced | 2024-03-01: Update information. |
Publication List
| Xia L, Liu JY, Yang MY, Zhang XH, Jiang Y, Yin QQ, Luo CH, Liu HC, Kang ZJ, Zhang CT, Gao BB, Zhou AW, Cai HY, Waller EK, Yan JS, Lu Y, Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells. Cancer Res, 84(3):479-492(2024) [pubmed] |
Keyword List
| submitter keyword: CD34, AML, CML, Tyr-phospho proteome, affinity MS |
Contact List
| Ying Lu | |
|---|---|
| contact affiliation | Shanghai Jiao Tong University School of Medicine |
| contact email | stove@shsmfu.edu.cn |
| lab head | |
| Li Xia | |
| contact affiliation | Shanghai Jiao Tong University School of Medicine |
| contact email | lixia@shsmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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