PXD023213

PXD023213 is an original dataset announced via ProteomeXchange.

Title	Analysis of the protein cargo of extracellular vesicles isolated from cultured line H9 human stem cells
Description	Extracellular vesicles (EV) are secreted by nearly every mammalian cell type and contain a wealth of bioactive cargo capable of modulating target cell physiology and function though a variety of paracrine signaling mechanisms (Leavitt et al., 2019). Human embryonic stem cell (hESC)-derived extracellular vesicles (hESC-derived EV), were extracted from the hESC line H9 (WA09 Wicell Research Institute, Inc., Madison, WI). We analyzed the bioactive protein cargo to identify components that help to resolve radiation-induced injury to the lung in mice when injected in vivo.
HostingRepository	PRIDE
AnnounceDate	2021-02-24
AnnouncementXML	Submission_2021-02-23_22:33:51.588.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Charles Limoli
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-18 01:48:13	ID requested
⏵ 1	2021-02-23 22:33:51	announced

Dataset with its publication pending

submitter keyword: Extracellular vesicles, Human embryonic stem cells, Proteomics, Radiation-injury, Lung fibrosis

Charles Limoli
contact affiliation	Dept. of Radiation Oncology, Medical Sciences I, B146B, University of California Irvine, CA 92697-2695
contact email	climoli@uci.edu
lab head
Charles Limoli
contact affiliation	University of California, Irvine
contact email	climoli@uci.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD023213

PRIDE project URI

• PRIDE
  1. PXD023213
     1. Label: PRIDE project
     2. Name: Analysis of the protein cargo of extracellular vesicles isolated from cultured line H9 human stem cells