PXD023182

PXD023182 is an original dataset announced via ProteomeXchange.

Title	N-terminal VP1 truncation favor T=1 norovirus-like particles
Description	Noroviruses cause immense sporadic gastroenteritis outbreaks worldwide. Upcoming genotypes, which are divided based on VP1 sequence, further enhance this public thread regularly. Self-assembling properties of the human norovirus major capsid protein VP1 are crucial for using virus-like particles (VLPs) for vaccine development. However, there is no vaccine available yet. Here, VLPs from different variants produced in insect cells are characterized in detail using a set of biophysical and structural tools.
HostingRepository	PRIDE
AnnounceDate	2021-01-11
AnnouncementXML	Submission_2021-01-11_11:31:50.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christoph Krisp
SpeciesList	scientific name: Norovirus; NCBI TaxID: 142786;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive; Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-16 09:15:13	ID requested
⏵ 1	2021-01-11 11:31:51	announced

Pogan R, Weiss VU, Bond K, D, ü, lfer J, Krisp C, Lyktey N, M, ü, ller-Guhl J, Zoratto S, Allmaier G, Jarrold MF, Mu, ñ, oz-Fontela C, Schl, ü, ter H, Uetrecht C, = 1 Norovirus-Like Particles. Vaccines (Basel), 9(1):(2020) [pubmed]

submitter keyword: norovirus, capsid assembly, VP1 truncation

Dr Charlotte Uetrecht
contact affiliation	Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg, Germany
contact email	charlotte.uetrech@leibniz-hpi.com
lab head
Christoph Krisp
contact affiliation	University Medical Center Hamburg-Eppendorf Institute of Clinical Chemistry and Laboratory Medicine Mass Spectrometric Proteomics
contact email	c.krisp@uke.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD023182

PRIDE project URI

• PRIDE
  1. PXD023182
     1. Label: PRIDE project
     2. Name: N-terminal VP1 truncation favor T=1 norovirus-like particles