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PXD023182

PXD023182 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleN-terminal VP1 truncation favor T=1 norovirus-like particles
DescriptionNoroviruses cause immense sporadic gastroenteritis outbreaks worldwide. Upcoming genotypes, which are divided based on VP1 sequence, further enhance this public thread regularly. Self-assembling properties of the human norovirus major capsid protein VP1 are crucial for using virus-like particles (VLPs) for vaccine development. However, there is no vaccine available yet. Here, VLPs from different variants produced in insect cells are characterized in detail using a set of biophysical and structural tools.
HostingRepositoryPRIDE
AnnounceDate2021-01-11
AnnouncementXMLSubmission_2021-01-11_11:31:50.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristoph Krisp
SpeciesList scientific name: Norovirus; NCBI TaxID: 142786;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentQ Exactive; Orbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-12-16 09:15:13ID requested
12021-01-11 11:31:51announced
Publication List
Pogan R, Weiss VU, Bond K, D, ü, lfer J, Krisp C, Lyktey N, M, ü, ller-Guhl J, Zoratto S, Allmaier G, Jarrold MF, Mu, ñ, oz-Fontela C, Schl, ü, ter H, Uetrecht C, = 1 Norovirus-Like Particles. Vaccines (Basel), 9(1):(2020) [pubmed]
Keyword List
submitter keyword: norovirus, capsid assembly, VP1 truncation
Contact List
Dr Charlotte Uetrecht
contact affiliationHeinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg, Germany
contact emailcharlotte.uetrech@leibniz-hpi.com
lab head
Christoph Krisp
contact affiliationUniversity Medical Center Hamburg-Eppendorf Institute of Clinical Chemistry and Laboratory Medicine Mass Spectrometric Proteomics
contact emailc.krisp@uke.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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