PXD023169

PXD023169 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Flash Oxidation (FOX) System: A Novel Laser-free Fast Photochemical Oxidation Protein Footprinting Platform
Description	To validate the FOX flash photolysis system for hydroxyl radical footprinting of proteins experiments, TNF-alpha was oxidized in the presence and absence of a specific monoclonal antibody, adalimumab. The peptides that show decrease in oxidation correlate well with the known epitope for adalimumab.
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-12_00:33:30.405.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sandeep Misra
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-16 01:31:45	ID requested
⏵ 1	2022-08-12 00:33:31	announced

Publication List

Sharp JS, Chea EE, Misra SK, Orlando R, Popov M, Egan RW, Holman D, Weinberger SR, Flash Oxidation (FOX) System: A Novel Laser-Free Fast Photochemical Oxidation Protein Footprinting Platform. J Am Soc Mass Spectrom, 32(7):1601-1609(2021) [pubmed]

Sharp JS, Chea EE, Misra SK, Orlando R, Popov M, Egan RW, Holman D, Weinberger SR, Flash Oxidation (FOX) System: A Novel Laser-Free Fast Photochemical Oxidation Protein Footprinting Platform. J Am Soc Mass Spectrom, 32(7):1601-1609(2021) [pubmed]

Keyword List

submitter keyword: FPOP, HRPF, Mass spectrometry, Flash photolysis, tumor necrosis factor-alpha

submitter keyword: FPOP, HRPF, Mass spectrometry, Flash photolysis, tumor necrosis factor-alpha

Contact List

Joshua Shane Sharp
contact affiliation	Department of BioMOlecular Sciences University of Mississippi
contact email	jsharp@olemiss.edu
lab head
Sandeep Misra
contact affiliation	University of Mississippi
contact email	skmisra@olemiss.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD023169
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD023169

PRIDE project URI

Repository Record List

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