PXD023166

PXD023166 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-enriched culture conditions
Description	The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were treated with anti-inflammatory cytokines in serum-enriched cell culture media, and analyzed by LC-MS/MS using an Orbitrap QE instrument.
HostingRepository	PRIDE
AnnounceDate	2021-10-07
AnnouncementXML	Submission_2021-10-07_00:07:49.441.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Iulia M. Lazar
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-16 01:31:32	ID requested
1	2021-10-06 16:02:08	announced
⏵ 2	2021-10-07 00:07:50	announced	2021-10-07: Updated project metadata.

Publication List

Ahuja S, Lazar IM, Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory Cytokines. Front Immunol, 12():646043(2021) [pubmed]
10.3389/FIMMU.2021.646043;

Ahuja S, Lazar IM, Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory Cytokines. Front Immunol, 12():646043(2021) [pubmed]

10.3389/FIMMU.2021.646043;

Keyword List

submitter keyword: HMC3, cytokines, tumor,Microglia

submitter keyword: HMC3, cytokines, tumor,Microglia

Contact List

Iulia Lazar
contact affiliation	Virginia Tech
contact email	malazar@vt.edu
lab head
Iulia M. Lazar
contact affiliation	Virginia Tech
contact email	malazar@vt.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD023166
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD023166

PRIDE project URI

Repository Record List

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