PXD023150

PXD023150 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomics identifies ML111 as a cell-cycle inhibitor
Description	We used quantitative mass spectrometry to analyze the effect of ML111 on the whole proteome of SK-N-MC cells. Results: ML111 treatment results in the accumulation of APC/C substrates suggesting that ML111 disrupts the cell cycle at or before the mitotic spindle assembly checkpoint.
HostingRepository	MassIVE
AnnounceDate	2021-09-16
AnnouncementXML	Submission_2021-09-16_09:42:32.433.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Walter K Vogel
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Acetyl; Carbamidomethyl; L-methionine sulfoxide; TMT6plex
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-15 13:03:59	ID requested
⏵ 1	2021-09-16 09:42:32	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Ewing sarcoma, ML111, quantitative mass spectroscopy, isobaric tag, drug discovery

submitter keyword: Ewing sarcoma, ML111, quantitative mass spectroscopy, isobaric tag, drug discovery

Contact List

Mark Leid
contact affiliation	Oregon State University
contact email	mark.leid@wsu.edu
lab head
Walter K Vogel
contact affiliation	Oregon State University
contact email	vogelw@oregonstate.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000086599/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000086599/