PXD023115

PXD023115 is an original dataset announced via ProteomeXchange.

Title	Differential roles of MARCH1 and MARCH8 E3 Ub ligases in haemopoietic and non-haemopoietic cell types.
Description	Using primary cells isolated from Marchf1-/- and Marchf8-/- mice, we have undertaken extensive analysis of MARCH1 and MARCH8 E3 Ub ligases in an array of primary haemopoietic and non-haemopoietic cell types including traditional and non-traditional antigen presenting cells (APCs). Using flow cytometry and proteomic analysis of plasma membrane (PM) and intracellular compartments (IC), we describe unique roles for MARCH1 and MARCH 8 in haemopoietic cells and non-haemopoietic cells respectively to redefine a panel of substrates for these E3 Ub ligases in primary immune cells.
HostingRepository	PRIDE
AnnounceDate	2022-01-20
AnnouncementXML	Submission_2022-01-20_01:02:18.425.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giuseppe Infusini
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-14 01:18:54	ID requested
⏵ 1	2022-01-20 01:02:18	announced

Dataset with its publication pending

submitter keyword: Immunoreceptors, Ubiquitination, Plasma Membrane Proteostasis

Jose A. Villadangos
contact affiliation	Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia. Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC 3010, Australia
contact email	j.villadangos@unimelb.edu.au
lab head
Giuseppe Infusini
contact affiliation	WEHI
contact email	infusini@wehi.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/01/PXD023115

PRIDE project URI

• PRIDE
  1. PXD023115
     1. Label: PRIDE project
     2. Name: Differential roles of MARCH1 and MARCH8 E3 Ub ligases in haemopoietic and non-haemopoietic cell types.