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PXD023006

PXD023006 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse cornea,sclera,skin LC-MSMS
DescriptionWe generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
HostingRepositoryPRIDE
AnnounceDate2026-03-02
AnnouncementXMLSubmission_2026-03-01_16:06:44.597.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD023006
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterYanling Liu
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList4-hydroxy-L-proline
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-12-09 00:21:26ID requested
12026-03-01 16:06:46announced
Publication List
10.1155/humu/9995099;
10.6019/PXD023006;
Liu Y, Dong S, Huang F, Li R, He X, Jiang Y, Tian Q, Xiong H, Jin L, Wang Q, Xia L, Chen J, Wu H, Guo H, Zhou X, Xia K, Hu Z, P4HA2 Participates in Pathogenesis of Refractive Error by Regulating Collagen Posttranslational Modification and Extracellular Matrix Balance. Hum Mutat, 2026():9995099(2026) [pubmed]
Keyword List
submitter keyword: skin LC-MSMS,Mouse cornea,sclera
Contact List
Zhengmao Hu
contact affiliationCentral South University
contact emailhuzhengmao@sklmg.edu.cn
lab head
Yanling Liu
contact affiliationCentral South University
contact email359959413@qq.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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