PXD022998

PXD022998 is an original dataset announced via ProteomeXchange.

Title	Evaluation of the p53 isoform Δ133p53β aggregation capacity
Description	p53 isoforms and particularly Δ133p53β play a critical role in cancer progression. We demonstrate that WT Δ133p53β activity is regulated through an aggregation-dependent mechanism. Creation of WT Δ133p53β aggregates depends on associations with specific interacting partners and was observed both in cancer cell lines and in human tumour biopsies.
HostingRepository	PRIDE
AnnounceDate	2021-06-04
AnnouncementXML	Submission_2021-06-04_02:33:04.235.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Functional Proteomics Platform FPP
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-08 07:29:13	ID requested
⏵ 1	2021-06-04 02:33:04	announced

Dataset with its publication pending

submitter keyword: p53 isoform,Δ133p53β, aggregation

Pierre Roux
contact affiliation	CRBM, CNRS, UMR5237, Montpellier
contact email	pierre.roux@crbm.cnrs.fr
lab head
Functional Proteomics Platform FPP
contact affiliation	FPP CNRS
contact email	contact@fpp.cnrs.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD022998

PRIDE project URI

• PRIDE
  1. PXD022998
     1. Label: PRIDE project
     2. Name: Evaluation of the p53 isoform Δ133p53β aggregation capacity