PXD022856 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Complexome profiling of mitochondrial protein complexes to study assembly of complex III and supercomplex stability in patients with defects in UQCRH gene |
Description | UQCRH, also called the hinge protein, is a small subunit of Ubiquinol—cytochrome-c reductase (complex III). Here we used a complexome analysis of primary and immortalized fibroblasts from patients with a homozygous 2 exon deletion in the UQCRH gene and analyzed complex III assembly and altered supercomplex composition. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-20 |
AnnouncementXML | Submission_2021-09-20_03:16:03.516.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ilka Wittig |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-12-01 23:11:45 | ID requested | |
⏵ 1 | 2021-09-20 03:16:03 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: complexome profiling, oxidative phosphorylation system, supercomplexes, complex III assembly |
Contact List
Robert Taylor |
contact affiliation | Highly Specialised Mitochondrial Diagnostic Laboratory, Wellcome Centre for Mitochondrial Research, Newcastle University, UK |
contact email | robert.taylor@ncl.ac.uk |
lab head | |
Ilka Wittig |
contact affiliation | Functional Proteomics, Goethe University, Frankfurt am Main , Germany |
contact email | wittig@med.uni-frankfurt.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
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[ - ]
- PRIDE
- PXD022856
- Label: PRIDE project
- Name: Complexome profiling of mitochondrial protein complexes to study assembly of complex III and supercomplex stability in patients with defects in UQCRH gene