PXD022774
PXD022774 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome-wide identification lncRNA CCAT1 directly binding proteins by RAP-MS |
Description | We purify and identify CCAT1 binding proteins by RAP-MS. As a result, we identified out more than 600 CCAT1 binding proteins and more than 60% of them are RNA binding proteins recorded by RBPs database EuRBPDB. Among the identified CCAT1 binding proteins, Vimentin is a crucial protein. Additionally, CCAT1 could positively influence the protein level of Vimentin and enhance migration and invasion ability of cancer cells. Our data indicate that CCAT1 may bind and stabilize Vimentin enhancing the migration and invasion ability of cancer Cell. |
HostingRepository | iProX |
AnnounceDate | 2020-11-26 |
AnnouncementXML | Submission_2023-10-26_19:12:27.610.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zhangfu Li |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-11-26 18:24:21 | ID requested | |
1 | 2020-11-26 18:38:53 | announced | |
⏵ 2 | 2023-10-26 19:12:28 | announced | 2023-10-27: Update publication information. |
Publication List
Li Z, Yuan J, Da Q, Yan Z, Qu J, Li D, Liu X, Zhan Q, Liu J, Long non-coding RNA colon cancer-associated transcript 1-Vimentin axis promoting the migration and invasion of HeLa cells. Chin Med J (Engl), 136(19):2351-2361(2023) [pubmed] |
Keyword List
submitter keyword: CCAT1, Vimentin, RAP-MS |
Contact List
Jikui Liu | |
---|---|
contact affiliation | Peking University Shenzhen Hospital |
contact email | Liu8929@126.com |
lab head | |
Zhangfu Li | |
contact affiliation | Peking University Shenzhen Hospital |
contact email | lizhf1990@sina.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |