PXD022606

PXD022606 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ac-IP tag enables multiplexed proteome quantification in data-independent acquisition mode
Description	We propose the isotopically labeled Ac-IP (acetyl-isoleucine-proline) tag for multiplexed quantification of peptides at the MS1 level in the data-independent acquisition (DIA) mode. Differentially labeled peptides have distinct precursor ions carrying the quantitative information but identical MS2 spectra. The isotopically labeled Ac-Ile part leaves as a neutral loss upon collision-induced dissociation (CID) while fragmentation of the peptide backbone generates information for peptide identification.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:22:40.577.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD022606
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Xiaobo Tian
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-18 08:03:58	ID requested
1	2021-06-06 23:42:06	announced
⏵ 2	2024-10-22 05:22:41	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD022606;
Tian X, de Vries MP, Permentier HP, Bischoff R, The Isotopic Ac-IP Tag Enables Multiplexed Proteome Quantification in Data-Independent Acquisition Mode. Anal Chem, 93(23):8196-8202(2021) [pubmed]
10.1021/acs.analchem.1c00453;

10.6019/PXD022606;

Tian X, de Vries MP, Permentier HP, Bischoff R, The Isotopic Ac-IP Tag Enables Multiplexed Proteome Quantification in Data-Independent Acquisition Mode. Anal Chem, 93(23):8196-8202(2021) [pubmed]

10.1021/acs.analchem.1c00453;

Keyword List

submitter keyword: Quantitative proteomics, isotope labeling, data-independent acquisition

submitter keyword: Quantitative proteomics, isotope labeling, data-independent acquisition

Contact List

Rainer Bischoff
contact affiliation	Department of Analytical Biochemistry and Interfaculty Mass Spectrometry Center, Groningen Research Institute of Pharmacy, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands
contact email	r.p.h.bischoff@rug.nl
lab head
Xiaobo Tian
contact affiliation	University of Groningen
contact email	tianxiaobo002@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD022606
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD022606

PRIDE project URI

Repository Record List

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