PXD022578 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Insights into the modes of action of tritium on zebrafish, Danio rerio, early-life stages, using proteomic analyses |
Description | Tritium is an ubiquist radionuclide which can be found in the environment due to natural and anthropogenic activities, particularly in aquatic ecosystems. In this context, tritium effects on aquatic species such as fish have to be characterized. HTO (tritiated water) effects were therefore investigated in zebrafish, Danio rerio, a common model in toxicology and ecotoxicology with a fully sequenced genome. Experiments were conducted on early life stages. Larvae were exposed to 0.4 and 4 mGy/h of HTO until 10 days post fertilization. Tritium internalization was quantified and effects were investigated using a proteomic analysis. The global analysis of the proteome was performed after protein extraction at 7 and 10 dpf on zebrafish eggs exposed from 3 hpf to 10 dpf. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:56:58.818.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Luc Camoin |
SpeciesList | scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-11-17 01:54:11 | ID requested | |
1 | 2024-08-29 06:42:42 | announced | |
⏵ 2 | 2024-10-22 06:56:59 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.jenvrad.2023.107141; |
Arcanjo C, Frelon S, Armant O, Camoin L, Audebert S, Camilleri V, Cavali, é I, Adam-Guillermin C, Gagnaire B, Insights into the modes of action of tritium on the early-life stages of zebrafish, Danio rerio, using transcriptomic and proteomic analyses. J Environ Radioact, 261():107141(2023) [pubmed] |
Keyword List
submitter keyword: Tritium |
zebrafish Danio rerio |
early-life stages |
proteomics |
Contact List
Luc Camoin |
contact affiliation | Marseille Protéomique, Inserm, CNRS, IPC |
contact email | luc.camoin@inserm.fr |
lab head | |
Luc Camoin |
contact affiliation | Life Sciences |
contact email | luc.camoin@inserm.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD022578
- Label: PRIDE project
- Name: Insights into the modes of action of tritium on zebrafish, Danio rerio, early-life stages, using proteomic analyses