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PXD022572

PXD022572 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProtein recruitment on chromatin in the presence or absence of Plk1
DescriptionPolo-like kinase 1 (Plk1) is an important protein kinase for checkpoint recovery and adaptation in response to DNA damage and replication stress. However, although Plk1 is present in S phase, little is known about its localization and function during unperturbed DNA replication. Here we used a previously described Chromatin Mass spectrometry (Chromass) protocol (Project PXD000490) to compare the protein recruitment on chromatin in Xenopus egg extracts during unperturbed DNA replication in the presence or after Plk1 depletion from the extract.
HostingRepositoryPRIDE
AnnounceDate2021-08-25
AnnouncementXMLSubmission_2021-08-25_06:55:36.622.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDavid Cornu
SpeciesList scientific name: Xenopus laevis (African clawed frog); NCBI TaxID: 8355;
ModificationListmonohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-17 01:53:39ID requested
12021-08-25 06:55:36announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Xenopus laevis, LCMSMS, Chromass
Contact List
David Cornu
contact affiliationUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France
contact emaildavid.cornu@i2bc.paris-saclay.fr
lab head
David Cornu
contact affiliationSICaPS, Institute of Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Univ. Paris-Saclay 91198 Gif-sur-Yvette Cedex, France
contact emaildavid.cornu@i2bc.paris-saclay.fr
dataset submitter
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Dataset FTP location
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