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PXD022402

PXD022402 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleWT/SIRT6 KO 293T cell AP-MS anti-CDH1-HA
DescriptionThe study found reciprocal regulation between SIRT6 and APC/C. While SIRT6 is ubiquitinated by APC/C and degraded, CDH1, a co-activator of APC/C, is also deacetylated by SIRT6 and degraded.
HostingRepositoryPRIDE
AnnounceDate2021-09-09
AnnouncementXMLSubmission_2021-09-09_14:06:43.867.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHelin Wang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-06 01:39:29ID requested
12021-09-09 14:06:44announced
Publication List
Wang H, Feng K, Wang Q, Deng H, Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. Sci Rep, 11(1):14253(2021) [pubmed]
Keyword List
submitter keyword: 293T, AP-MS, acetylation
Contact List
Haiteng Deng
contact affiliationSchool of Life Sciences, Tsinghua University
contact emaildht@mail.tsinghua.edu.edu
lab head
Helin Wang
contact affiliationTsinghua University
contact emailwhl0818@live.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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