PXD022342
PXD022342 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Renal redox proteomic analysis of Memo1-dependent FGF23-driven cell signaling |
Description | Memo is a copper-dependent redox enzyme modulating receptor tyrosine kinase signaling by unknown mechanisms (Meira et al., Nat Cell Biol 2004; MacDonald et al., Science Signal 2014). Memo1 deletion causes a phenotype partially resembling Klotho and Fgf23-deficient mice (Haenzi et al., FASEB J 2014; Moor et al., JBMR Plus 2018). To delineate potential effects of Memo redox function on FGF23-driven cellular signaling processes, we performed a redox proteomics screen in kidney of whole-body Memo-deficient and control mice treated with recombinant FGF23 or vehicle. |
HostingRepository | MassIVE |
AnnounceDate | 2020-11-04 |
AnnouncementXML | Submission_2020-11-04_02:29:10.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Matthias Moor |
SpeciesList | scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | instrument model |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-11-04 02:21:49 | ID requested | |
⏵ 1 | 2020-11-04 02:29:11 | announced |
Publication List
no publication |
Keyword List
submitter keyword: Memo1, redox signaling, cysteine oxidation |
Contact List
Matthias Moor | |
---|---|
contact affiliation | University Hospital Bern |
contact email | matthias.moor@dbmr.unibe.ch |
lab head | |
Matthias Moor | |
contact affiliation | University Hospital Bern |
contact email | matthias.moor@dbmr.unibe.ch |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
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