PXD022305
PXD022305 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined the sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals |
Description | This study performed the comprehensive mass spectrometric analyses of O-GlcNAc glycans on NOTCH1 in mammalian cultured cells. The results indicated that the O-GlcNAcylation occurs only a subset of EGF repeats harboring putative O-GlcNAcylation sites, refining the sequons for extracellular O-GlcNAcylation in mammals. Moreover, novel structures with fucosylated O-GlcNAc glycans were identified and the similar structure was detected on O-fucose glycans, extending the view of structural diversity of functional Notch O-glycans. |
HostingRepository | jPOST |
AnnounceDate | 2020-11-03 |
AnnouncementXML | Submission_2022-09-18_02:15:47.383.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mitsutaka Ogawa |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-11-02 20:23:36 | ID requested | |
1 | 2020-11-02 20:23:40 | announced | |
2 | 2021-02-04 17:00:56 | announced | 2021-02-04: Updated FTP location. |
⏵ 3 | 2022-09-18 02:15:47 | announced | 2022-09-18: Updated FTP location. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: O-GlcNAc, Notch, fucosyltransferases, EOGT, Lewis X |
Contact List
Tetsuya Okajima | |
---|---|
lab head | |
Mitsutaka Ogawa | |
contact affiliation | Nagoya University School of Medicine |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000997/ |