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PXD022305

PXD022305 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined the sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals
DescriptionThis study performed the comprehensive mass spectrometric analyses of O-GlcNAc glycans on NOTCH1 in mammalian cultured cells. The results indicated that the O-GlcNAcylation occurs only a subset of EGF repeats harboring putative O-GlcNAcylation sites, refining the sequons for extracellular O-GlcNAcylation in mammals. Moreover, novel structures with fucosylated O-GlcNAc glycans were identified and the similar structure was detected on O-fucose glycans, extending the view of structural diversity of functional Notch O-glycans.
HostingRepositoryjPOST
AnnounceDate2020-11-03
AnnouncementXMLSubmission_2022-09-18_02:15:47.383.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMitsutaka Ogawa
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-02 20:23:36ID requested
12020-11-02 20:23:40announced
22021-02-04 17:00:56announced2021-02-04: Updated FTP location.
32022-09-18 02:15:47announced2022-09-18: Updated FTP location.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: O-GlcNAc, Notch, fucosyltransferases, EOGT, Lewis X
Contact List
Tetsuya Okajima
lab head
Mitsutaka Ogawa
contact affiliationNagoya University School of Medicine
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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