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PXD022303

PXD022303 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleULK1 regulated phosphosites in mouse and human cells
Description(1)In vivo SILAC analyses of mouse embryonic fibroblasts (MEFs, triple labeling) were performed comparing phosphorylation events. ULK1 double knock out MEFs (VC) were compared to double knock out MEFs expressing human ULK1 (RE) in fed (DMEM) and starvation (HBSS) conditions. (2) In vivo SILAC analyses of A549 cells (triple labeling) were performed comparing phosphorylation events (195 raw files labeled ""A549""). A549 cells in fed conditions (DMEM) were compared to starved cells (HBSS) and cells treated with rapamycin (Rapa).
HostingRepositoryPRIDE
AnnounceDate2021-11-03
AnnouncementXMLSubmission_2021-11-03_05:27:02.614.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoern Dengjel
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-02 09:06:25ID requested
12021-11-03 05:27:03announced
Publication List
Hu Z, Sankar DS, Vu B, Leytens A, Vionnet C, Wu W, Stumpe M, Mart, í, nez-Mart, í, nez E, Stork B, Dengjel J, ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy. Cell Rep, 36(13):109762(2021) [pubmed]
Keyword List
submitter keyword: autophagy, MEFs, A549, phosphoproteomics, SILAC
Contact List
Joern Dengjel
contact affiliationDepartment of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 E joern.dengjel@unifr.ch
contact emailjoern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliationUniversity of Fribourg
contact emailjoern.dengjel@medizin.uni-freiburg.de
dataset submitter
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Dataset FTP location
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