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PXD022287

PXD022287 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA dataset for training/testing machine learning models of peptide feature detection: Human HELA LC-MSMS
DescriptionWe introduce MSTracer, a tool for peptide feature detection from MS1, which incorporates a machine-learning-combined scoring function based on peptide isotopic distribution and peptide intensity shape on the LC-MS map. By using Support Vector Regression (SVR), the quality of detected peptide features is remarkably improved. By utilising Neural Networks (NN), scores that indicate the quality of features are assigned for detected features as well. We use the Human HELA LC-MSMS dataset to train and test the results and compare with MaxQuant, OpenMS, and Dinosaur.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:23:02.803.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD022287
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterXiangyuan Zeng
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized amino-terminal residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-02 01:42:03ID requested
12021-06-17 20:20:52announced
22023-11-14 08:52:54announced2023-11-14: Updated project metadata.
32024-10-22 05:23:03announced2024-10-22: Updated project metadata.
Publication List
10.1021/ACS.JPROTEOME.0C01029;
Keyword List
ProteomeXchange project tag: deep learning, benchmarking, machine learning
submitter keyword: Human, LC-MS/MS
Contact List
Bin Ma
contact affiliationUniversity of Waterloo
contact emailbin.ma@uwaterloo.ca
lab head
Xiangyuan Zeng
contact affiliationUniversity of Waterloo
contact emailx25zeng@uwaterloo.ca
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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