PXD022120

PXD022120 is an original dataset announced via ProteomeXchange.

Title	HYPK affects proteostasis by facilitating co-translational imprinting of the proteome with acetylation marks
Description	N-terminal acetylation is one of the most common protein modifications in eukaryotes. The NatA complex is the dominant regulator of the N-acetylome in all eukaryotes. The Huntingtin yeast partner K (HYPK) physically interacts with the NatA/NAA50 comples in metazoan and we describe HYPK as a critical regulator of NatA acivity. This proteome dataset compares the HYPK mutation Arabidopsis lines hypk-1 and hypk-3 to wild type Arabidopsis.
HostingRepository	PRIDE
AnnounceDate	2022-04-13
AnnouncementXML	Submission_2022-04-13_03:33:15.088.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mario Oroshi
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-21 06:40:14	ID requested
⏵ 1	2022-04-13 03:33:15	announced

Dataset with its publication pending

submitter keyword: N-terminal acetylation

Prof. Dr. Matthias Mann
contact affiliation	Dept. Proteomics and Signal Transduction Max Planck Institute of Biochemistry
contact email	mmann@biochem.mpg.de
lab head
Mario Oroshi
contact affiliation	Proteomics
contact email	oroshi@biochem.mpg.de
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD022120
     1. Label: PRIDE project
     2. Name: HYPK affects proteostasis by facilitating co-translational imprinting of the proteome with acetylation marks