PXD022109 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Parkin is an E3 ligase for the ubiquitin-like modifier Fat10 which inhibits Parkin activation and mitophagy |
Description | Parkin is an E3 ubiquitin ligase belonging to the RING-between-RING family. Mutations in the Parkin-encoding gene PARK2 are associated with familial Parkinson’s Disease. Here, we investigate the interplay between Parkin / Parkin-S65P and the inflammatory cytokine-induced ubiquitin-like modifier FAT10. |
HostingRepository | PRIDE |
AnnounceDate | 2021-03-05 |
AnnouncementXML | Submission_2021-03-04_22:39:00.235.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Florian Stengel |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | crosslinked residues; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-10-21 02:33:39 | ID requested | |
⏵ 1 | 2021-03-04 22:39:00 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Fat10, ubiquitin, Parkin, mitophagy, Parkinson’s Disease |
Contact List
Florian Stengel |
contact affiliation | Department of Biology, University of Konstanz, 78457 Konstanz, Germany |
contact email | florian.stengel@uni-konstanz.de |
lab head | |
Florian Stengel |
contact affiliation | Universität Konstanz |
contact email | florian.stengel@uni-konstanz.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD022109
- Label: PRIDE project
- Name: Parkin is an E3 ligase for the ubiquitin-like modifier Fat10 which inhibits Parkin activation and mitophagy