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PXD022109

PXD022109 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleParkin is an E3 ligase for the ubiquitin-like modifier Fat10 which inhibits Parkin activation and mitophagy
DescriptionParkin is an E3 ubiquitin ligase belonging to the RING-between-RING family. Mutations in the Parkin-encoding gene PARK2 are associated with familial Parkinson’s Disease. Here, we investigate the interplay between Parkin / Parkin-S65P and the inflammatory cytokine-induced ubiquitin-like modifier FAT10.
HostingRepositoryPRIDE
AnnounceDate2021-03-05
AnnouncementXMLSubmission_2021-03-04_22:39:00.235.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFlorian Stengel
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListcrosslinked residues; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-10-21 02:33:39ID requested
12021-03-04 22:39:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Fat10, ubiquitin, Parkin, mitophagy, Parkinson’s Disease
Contact List
Florian Stengel
contact affiliationDepartment of Biology, University of Konstanz, 78457 Konstanz, Germany
contact emailflorian.stengel@uni-konstanz.de
lab head
Florian Stengel
contact affiliationUniversität Konstanz
contact emailflorian.stengel@uni-konstanz.de
dataset submitter
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Dataset FTP location
PRIDE project URI
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