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PXD021988

PXD021988 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman, bronchoalveolar lavage, extracellular vesicles
DescriptionThe aim of the project was to explore large extracellular vesicles capacity to seperate non lung cancer from lung cancer cases. A case control study of patients suspected for lung cancer (12 non lung cancer and 12 lung cancers). The raw files are labeled according to clinical status. Small and large extracellular vesicles were isolated by differential centrifugation. The proteome of full BAL, vesicle depleted BAL, small and large extracellular vesicles were characterized by LC-MS. Small extracellular vesicles were further analyzed by nanoparticle tracking analysis, Transmission electron microscopy and western blots.
HostingRepositoryPRIDE
AnnounceDate2020-12-15
AnnouncementXMLSubmission_2020-12-15_04:07:44.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRune Matthiesen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-10-14 23:37:11ID requested
12020-12-15 04:07:45announced
Publication List
Carvalho AS, Moraes MCS, Hyun Na C, Fierro-Monti I, Henriques A, Zahedi S, Bodo C, Tranfield EM, Sousa AL, Farinho A, Rodrigues LV, Pinto P, B, á, rbara C, Mota L, Abreu TT, Semedo J, Seixas S, Kumar P, Costa-Silva B, Pandey A, Matthiesen R, Is the Proteome of Bronchoalveolar Lavage Extracellular Vesicles a Marker of Advanced Lung Cancer? Cancers (Basel), 12(11):(2020) [pubmed]
Keyword List
submitter keyword: bronchoalveolar lavage, lung cancer, extracellular vesicles
Contact List
Rune Matthiesen
contact affiliationComputational and Experimental Biology Group, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Faculdade de Ciencias Medicas, Universidade NOVA de Lisboa, Campo dos Martires da Patria, 130, 1169-056 Lisboa, Portugal
contact emailrunem2009@gmail.com
lab head
Rune Matthiesen
contact affiliationComputational and Experimental Biology Group, CEDOC NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS UNIVERSIDADE NOVA DE LISBOA Rua Câmara Pestana, 6-6A | 1150-082 Lisboa Portugal
contact emailrunem2009@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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