PXD021958

PXD021958 is an original dataset announced via ProteomeXchange.

Title	Mass spectrometry of human A549 cells transfected with EBV BRLF1
Description	The immediate-early protein BRLF1 plays important roles in lytic infection of Epstein-Barr virus (EBV), in which it activates lytic viral transcription and replication. However, knowledge of the influence of BRLF1 on cellular gene expression and transcriptional reprogramming during the early lytic cycle remains limited. Analysis of BRLF1-binding proteins by mass spectrometry would show what transcription factors BRLF1 binds to and would help us better understand how BRLF1 regulates human and viral genome during lytic infection.
HostingRepository	iProX
AnnounceDate	2020-10-13
AnnouncementXML	Submission_2023-03-02_18:27:34.883.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xubing Long
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-13 19:08:42	ID requested
1	2020-10-13 19:11:45	announced
⏵ 2	2023-03-02 18:27:35	announced	2023-03-03: Update publication information.

Long X, Yang J, Zhang X, Yang Z, Li Y, Wang F, Li X, Kuang E, BRLF1 suppresses RNA Pol III-mediated RIG-I inflammasome activation in the early EBV lytic lifecycle. EMBO Rep, 22(1):e50714(2021) [pubmed]

submitter keyword: human cell EBV BRLF1

Ersheng Kuang
contact affiliation	Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China
contact email	kuangersh@mail.sysu.edu.cn
lab head
Xubing Long
contact affiliation	Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China
contact email	longxb3@mail2.sysu.edu.cn
dataset submitter

iProX dataset URI