PXD021908

PXD021908 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Multiple Reaction Monitoring-based Assay for the Targeted Quantitation of Aberrant Substrate-specific Kinase Activity in Non-small Cell Lung Cancer
Description	Personalized tissue phosphoproteome was carried to target aberrant signaling in NSCLC from pairs of cancerous tissues and their adjacent normal counterparts from 5 patients. We then report a substrate-specific kinase assay based on multiple reaction monitoring mass spectrometer platform was then developed for relative and absolute quantification of substrate-specific kinase activity at the sensitivity of nanomolar kinase and nanogram cell lysate.
HostingRepository	jPOST
AnnounceDate	2021-10-11
AnnouncementXML	Submission_2022-09-18_03:52:54.727.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aaron James Reyes
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-10 21:05:02	ID requested
1	2021-10-10 08:00:04	announced
⏵ 2	2022-09-18 03:52:55	announced	2022-09-18: Updated FTP location.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: substrate-specific kinase activity, multiple reaction monitoring, phosphorylation site biomarkers, non-small cell lung cancer

submitter keyword: substrate-specific kinase activity, multiple reaction monitoring, phosphorylation site biomarkers, non-small cell lung cancer

Contact List

Yu-Ju Chen
lab head
Aaron James Reyes
contact affiliation	Institute of Chemistry, Academia Sinica
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000979/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000979/