PXD021871

PXD021871 is an original dataset announced via ProteomeXchange.

Title	Direct detection of SARS-CoV-2 viral antigens from urine samples by mass spectrometry
Description	SARS-CoV-2 infection has become a major public health burden and is known to affect many organs with the respiratory system being involved in a majority of cases. Here we undertook a mass spectrometry-based proteomic approach to test whether viral proteins could be detected in urine of patients with COVID-19. Urine samples from 39 patients positive for SARS-CoV-2 by RT-PCR were analysed by mass spectrometry. We detected peptides from the nucleocapsid protein of the SARS-CoV-2 virus in 13 out of 39 urine samples. Thus, our findings suggest that viral proteins present in the urine can be detected by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2021-05-19
AnnouncementXML	Submission_2021-05-19_11:08:51.753.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Akhilesh Pandey
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-07 01:18:25	ID requested
⏵ 1	2021-05-19 11:08:52	announced

Dataset with its publication pending

ProteomeXchange project tag: Covid-19

submitter keyword: SARS-CoV-2, Urine, Mass Spectrometry, Infectious Diseases, Pandemic

Prof. Akhilesh Pandey
contact affiliation	Department of Laboratory Medicine and Pathology & Center for Individualized Medicine Mayo Clinic Rochester MN 55905, USA
contact email	pandey.akhilesh@mayo.edu
lab head
Akhilesh Pandey
contact affiliation	Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905
contact email	pandey.akhilesh@mayo.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD021871

PRIDE project URI

• PRIDE
  1. PXD021871
     1. Label: PRIDE project
     2. Name: Direct detection of SARS-CoV-2 viral antigens from urine samples by mass spectrometry