PXD021803 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis |
Description | Here we investigate the possible relationship between the propagation of epigenetic information and the developmental cell proliferation during Xenopus embryogenesis. We systemically inhibited cell proliferation during the G1/S-transition in gastrula embryos and followed their development until the tadpole stage. We quantified by mass spectrometry the abundance of a large set of histone modification states, which reflects the developmental maturation of the embryonic epigenome. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:24:25.713.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Daniil Pokrovsky |
SpeciesList | scientific name: Xenopus laevis (African clawed frog); NCBI TaxID: 8355; |
ModificationList | monomethylated residue; phosphorylated residue; acetylated residue; dimethylated residue; N6,N6,N6-trimethyl-L-lysine |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-10-04 23:20:37 | ID requested | |
1 | 2024-10-07 13:36:10 | announced | |
⏵ 2 | 2024-10-22 05:24:26 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Histone modification |
epigenetics |
cell cycle |
Xenopus |
development |
Contact List
Ralph AW Rupp |
contact affiliation | Molecular Biology, Ludwig-Maximilians-Universitat Munchen |
contact email | ralph.rupp@bmc.med.lmu.de |
lab head | |
Daniil Pokrovsky |
contact affiliation | Ludwig Maximilian University of munich, BMC |
contact email | D.Pokrovsky@med.uni-muenchen.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021803
- Label: PRIDE project
- Name: Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis