PXD021797

PXD021797 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Trypannosome brucei brucei 427 TbTPR86 pullout
Description	TPR86 is a tetra tricopeptide repeat containing protein, which we detected by the pull out experiment of TbSkp-Z, which involves in the regulation of surface proteome changes and suramin seisitivity. In this previous experiments, a deubiquitylase, USP7 was detected as a complex member with strong affinity. This is reverse pullout to confirm the TUS (TPR86, USP7, SKP-Z) complex members.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_07:44:18.879.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kayo Ono
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-02 04:18:10	ID requested
⏵ 1	2025-05-06 07:44:19	announced

Publication List

10.3389/fpara.2023.1118284;
Yamada K, Zhang N, Yaqub FK, Zoltner M, Field MC, TUSK: a ubiquitin hydrolase complex modulating surface protein abundance in trypanosomes. Front Parasitol, 2():1118284(2023) [pubmed]

10.3389/fpara.2023.1118284;

Yamada K, Zhang N, Yaqub FK, Zoltner M, Field MC, TUSK: a ubiquitin hydrolase complex modulating surface protein abundance in trypanosomes. Front Parasitol, 2():1118284(2023) [pubmed]

Keyword List

submitter keyword: pulldown, skp1, pullout, TPR, brucei,Trypanosome, USP7

submitter keyword: pulldown, skp1, pullout, TPR, brucei,Trypanosome, USP7

Contact List

Mark C Field
contact affiliation	Professor of Cell Biology and Parasitology, FRSB Biological Chemistry and Drug Discovery Wellcome Centre for Anti-Infectives Research (WCAIR) School of Life Sciences University of Dundee MSI/WTB/JBC Complex Dow Street DUNDEE DD1 5EH, UK +44 (0)751-550-7880 mfield@mac.com
contact email	mfield@mac.com
lab head
Kayo Ono
contact affiliation	Postdoctoral research associate
contact email	k.ono@dundee.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD021797
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD021797

PRIDE project URI

Repository Record List

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