PXD021768

PXD021768 is an original dataset announced via ProteomeXchange.

Title	Identification of human GRHL1 interactors and post-translational modifications by LC-MS/MS
Description	Aim of the project was to identify interactors and post-translational modifications of recombinant 3xFLAG-6xHis-tagged human GRHL1, tandem-affinity purified from isolated HEK293 nuclei treated with DMSO as control or with the phytochemical papaverine.
HostingRepository	PRIDE
AnnounceDate	2021-11-02
AnnouncementXML	Submission_2022-01-24_02:54:19.805.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabian Fischer
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; ubiquitinylated lysine; phosphorylated residue; monohydroxylated residue; acetylated residue; dimethylated residue
Instrument	Q Exactive; nanoACQUITY UPLC

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-30 23:32:17	ID requested
1	2021-11-02 06:59:40	announced
⏵ 2	2022-01-24 02:54:20	announced	2022-01-24: Updated publication reference for PubMed record(s): 35013237.

Grigolon G, Araldi E, Erni R, Wu JY, Thomas C, La Fortezza M, Laube B, P, ö, hlmann D, Stoffel M, Zarse K, Carreira EM, Ristow M, Fischer F, Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan. Nat Commun, 13(1):107(2022) [pubmed]

submitter keyword: Interactors, Transcription Factor, Post-translational modification,GRHL1, LC-MS/MS

Michael Ristow
contact affiliation	Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, CH-8603, Switzerland
contact email	michael-ristow@ethz.ch
lab head
Fabian Fischer
contact affiliation	Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, CH-8603, Switzerland
contact email	ffischer@ffischer.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD021768

PRIDE project URI

• PRIDE
  1. PXD021768
     1. Label: PRIDE project
     2. Name: Identification of human GRHL1 interactors and post-translational modifications by LC-MS/MS