PXD021755

PXD021755 is an original dataset announced via ProteomeXchange.

Title	Identification of HLA class I-presented peptides in MSI CRC model cell line HCT-116
Description	HCT-116 cells were treated either with 5 µM of the NMD inhibitor 5-azacytidine (PMID: 25319547) or DMSO (negative solvent control) for 24 h to examine differences in HLA class I-mediated peptide presentation. Moreover, data were used for the identification of tumor-specific neoepitopes originating from insertion/deletion mutations due to microsatellite instability.
HostingRepository	PRIDE
AnnounceDate	2021-04-14
AnnouncementXML	Submission_2021-04-14_01:17:06.042.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jonas Becker
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-30 00:58:47	ID requested
⏵ 1	2021-04-14 01:17:06	announced

Dataset with its publication pending

submitter keyword: immunopeptidomics, HLA, colorectal cancer, microsatellite instability

Andreas E. Kulozik
contact affiliation	Molecular Medicine Partnership Unit (MMPU), Heidelberg University & European Molecular Biology Laboratory (EMBL) Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University & Hopp Children’s Cancer Center, National Center for Tumor Diseases (NCT)
contact email	andreas.kulozik@med.uni-heidelberg.de
lab head
Jonas Becker
contact affiliation	Molecular Medicine Partnership Unit (MMPU), Heidelberg University & European Molecular Biology Laboratory (EMBL); Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University & Hopp Children`s Cancer Center, National Center for Tumor Diseases (NCT)
contact email	jonas.becker@med.uni-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD021755

PRIDE project URI

• PRIDE
  1. PXD021755
     1. Label: PRIDE project
     2. Name: Identification of HLA class I-presented peptides in MSI CRC model cell line HCT-116