PXD021718

PXD021718 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteome of systemic extracellular vesicles from sporadic and familiar Alzheimer’s disease
Description	Evidence suggests that extracellular vesicles (EVs) act as mediators and biomarkers of neurodegenerative diseases. Two distinct forms of Alzheimer Disease (AD) are known: a late-onset sporadic form (SAD) and an early-onset familial form (FAD). This project aims to characterize and compare the protein profile of systemic EVs from postmortem SAD and FAD patients and compared them to postmortem controls. We used LC-MS/MS label-free analysis.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:29:06.036.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rafael Posada-Duque
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-28 06:21:41	ID requested
1	2021-09-09 07:36:10	announced
⏵ 2	2024-10-22 05:29:07	announced	2024-10-22: Updated project metadata.

Publication List

10.3389/fnagi.2020.587989;
Villar-Vesga J, Henao-Restrepo J, Voshart DC, Aguillon D, Villegas A, Casta, ñ, o D, Arias-Londo, ñ, o JD, Zuhorn IS, Ribovski L, Barazzuol L, Cardona-G, ó, mez GP, Posada-Duque R, Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer's Disease Leads to Neuroglial and Endothelial Cell Degeneration. Front Aging Neurosci, 12():587989(2020) [pubmed]

10.3389/fnagi.2020.587989;

Villar-Vesga J, Henao-Restrepo J, Voshart DC, Aguillon D, Villegas A, Casta, ñ, o D, Arias-Londo, ñ, o JD, Zuhorn IS, Ribovski L, Barazzuol L, Cardona-G, ó, mez GP, Posada-Duque R, Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer's Disease Leads to Neuroglial and Endothelial Cell Degeneration. Front Aging Neurosci, 12():587989(2020) [pubmed]

Keyword List

submitter keyword: extracellular vesicles, plasma, sporadic and familiar Alzheimer’s, LC-MS/MS

submitter keyword: extracellular vesicles, plasma, sporadic and familiar Alzheimer’s, LC-MS/MS

Contact List

Rafael Andres Posada-Duque
contact affiliation	1 Neuroscience Group of Antioquia, Cellular and Molecular Neurobiology Area, Faculty of Medicine, SIU, University of Antioquia, Calle 70, No. 52-21, Medellin, Colombia. 2 Institute of Biology, Faculty of Exact and Natural Sciences, University of Antioquia, Medellin, Colombia.
contact email	rafael.posada@udea.edu.co
lab head
Rafael Posada-Duque
contact affiliation	Institute of Biology, Faculty of Exact and Natural Sciences, University of Antioquia Medellin, Colombia
contact email	rafael.posada@udea.edu.co
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD021718
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD021718

PRIDE project URI

Repository Record List

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