PXD021700
PXD021700 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Histone PTMs dataset for Hyposuccinylation Derived from Abnormal Metabolism Promotes the Cell Migration of Esophageal Squamous Cell Cancer |
Description | We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead to this phenomenon. |
HostingRepository | iProX |
AnnounceDate | 2020-09-26 |
AnnouncementXML | Submission_2023-03-01_23:11:54.846.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zhenchang Guo |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | acetylated residue; methylthiolated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-09-27 20:20:57 | ID requested | |
1 | 2020-09-27 20:41:56 | announced | |
⏵ 2 | 2023-03-01 23:11:56 | announced | 2023-03-02: Update publication information. |
Publication List
Guo Z, Pan F, Peng L, Tian S, Jiao J, Liao L, Lu C, Zhai G, Wu Z, Dong H, Xu X, Wu J, Chen P, Bai X, Lin D, Xu L, Li E, Zhang K, Systematic Proteome and Lysine Succinylome Analysis Reveals Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Carcinoma. Mol Cell Proteomics, 20():100053(2021) [pubmed] |
Keyword List
submitter keyword: Lysine succinylation, acetylation, phosphorylation, ESCC, proteomics, histone PTMs |
Contact List
Kai Zhang | |
---|---|
contact affiliation | Department of Biochemistry and Molecular Biology, Tianjin Medical University |
contact email | kzhang@tmu.edu.cn |
lab head | |
Zhenchang Guo | |
contact affiliation | Tianjin Medical University |
contact email | guozhenchang@tmu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |