PXD021672

PXD021672 is an original dataset announced via ProteomeXchange.

Title	Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells
Description	Immunopeptidomic profiling of HLA-DR diverse monocyte-derived dendritic cells pulsed with SARS-CoV-2 spike (S) protein.
HostingRepository	PRIDE
AnnounceDate	2021-07-09
AnnouncementXML	Submission_2021-07-09_08:29:33.161.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD021672
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Robert Parker
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	amidated residue; methylthiolated residue; cysteinylation (disulfide with free L-cysteine); biotinylated residue; phosphorylated residue; homoserine; acetylated residue; monohydroxylated residue; deamidated residue; L-cysteine glutathione disulfide
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-24 06:19:48	ID requested
⏵ 1	2021-07-09 08:29:34	announced

Parker R, Partridge T, Wormald C, Kawahara R, Stalls V, Aggelakopoulou M, Parker J, Powell Doherty R, Ariosa Morejon Y, Lee E, Saunders K, Haynes BF, Acharya P, Thaysen-Andersen M, Borrow P, Ternette N, Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells. Cell Rep, 35(8):109179(2021) [pubmed]

Parker R, Partridge T, Wormald C, Kawahara R, Stalls V, Aggelakopoulou M, Parker J, Doherty RP, Morejon YA, Lee E, Saunders K, Haynes BF, Acharya P, Thaysen-Andersen M, Borrow P, Ternette N, Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells. bioRxiv, ():(2020) [pubmed]

ProteomeXchange project tag: Sars-cov-2

submitter keyword: SARS-CoV-2

coronavirus spike protein

receptor binding domain

Human leukocyte antigen Class II

HLA-II

peptide presentation

post-translational modification

glycosylation

antigen processing

receptor binding domain

immunopeptidomics

Nicola Ternette
contact affiliation	Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, United Kingdom
contact email	nicola.ternette@ndm.ox.ac.uk
lab head
Robert Parker
contact affiliation	Jenner Institute
contact email	robert.rparker@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD021672

PRIDE project URI

• PRIDE
  1. PXD021672
     1. Label: PRIDE project
     2. Name: Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells