PXD021630

PXD021630 is an original dataset announced via ProteomeXchange.

Title	Olfactory proteomics in amyotrophic lateral sclerosis
Description	Despite smell impairment has been considered a potential non-motor finding in ALS, the pathobiochemistry at olfactory level remains unknown. Here, we applied an olfactory quantitative proteotyping approach to analyze the magnitude of the olfactory bulb (OB) proteostatic imbalance in ALS subjects (n=12) respect to controls (n=8).
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_08:46:03.808.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Enrique Santamaría
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-22 09:06:56	ID requested
⏵ 1	2021-09-09 08:46:04	announced

Lach, é, n-Montes M, Mendizuri N, Ausin K, Andr, é, s-Benito P, Ferrer I, Fern, á, ndez-Irigoyen J, Santamar, í, a E, Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis. Int J Mol Sci, 21(21):(2020) [pubmed]

submitter keyword: olfactory bulb, proteomics, amyotrophic lateral slcerosis, olfactory marker protein

Enrique Santamaria
contact affiliation	Proteomics unit, Proteored-ISCIII Navarrabiomed, Pamplona, Spain
contact email	esantamma@navarra.es
lab head
Enrique Santamaría
contact affiliation	Proteomics unit
contact email	esantamma@navarra.es
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD021630
     1. Label: PRIDE project
     2. Name: Olfactory proteomics in amyotrophic lateral sclerosis