PXD021560

PXD021560 is an original dataset announced via ProteomeXchange.

Title	Trypanosoma brucei rhodensience suramin resistance shotgun proteomics
Description	Human African Trypanosomiasis (HAT) is a disease of major economic importance in Sub-Saharan Africa. In eastern and southern Africa. Here we analysed clinical isolates of T brucei rhodensiense, resistant to suramin by shotgun proteomics . And identified parasite proteins whose expression is associated with resistance to suramin.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_08:03:09.876.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Martin Rono
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-18 03:30:28	ID requested
⏵ 1	2021-09-09 08:03:10	announced

Mutuku CN, Bateta R, Rono MK, Njunge JM, Awuoche EO, Ndung'u K, Mang'era CM, Akoth MO, Adung'a VO, Ondigo BN, Mireji PO, Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda. Int J Parasitol Drugs Drug Resist, 15():57-67(2021) [pubmed]

submitter keyword: T brucei rhodesience, suramin resistance, proteomics

Martin rono
contact affiliation	KEMRI Wellcome Trust
contact email	mrono@kemri-wellcome.org
lab head
Martin Rono
contact affiliation	KEMRI
contact email	mrono@kemri-wellcome.org
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD021560
     1. Label: PRIDE project
     2. Name: Trypanosoma brucei rhodensience suramin resistance shotgun proteomics