PXD021517

PXD021517 is an original dataset announced via ProteomeXchange.

Title	Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins
Description	The aim of the MS analysis is to identify fatty acids modifying Cys3 of GNAI3. Detailed description in the manuscript Nuskova et al. submitted to NatComms.
HostingRepository	PRIDE
AnnounceDate	2021-07-22
AnnouncementXML	Submission_2021-08-26_06:16:27.458.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hana Nuskova
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	palmitoylated residue; myristoylated residue; iodoacetamide derivatized residue
Instrument	ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-16 08:15:23	ID requested
1	2021-07-21 22:02:50	announced
⏵ 2	2021-08-26 06:16:28	announced	2021-08-26: Updated publication reference for PubMed record(s): 34321466.

N, ů, skov, á H, Serebryakova MV, Ferrer-Caelles A, Sachsenheimer T, L, ü, chtenborg C, Miller AK, Br, ü, gger B, Kordyukova LV, Teleman AA, Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins. Nat Commun, 12(1):4590(2021) [pubmed]

submitter keyword: GNAI3, acylation, stearoylation, oleoylation

Aurelio A. Teleman
contact affiliation	Division of Signal Transduction in Cancer and Metabolism, German Cancer Research Centre (DKFZ), Heidelberg, Germany
contact email	a.teleman@dkfz-heidelberg.de
lab head
Hana Nuskova
contact affiliation	DKFZ Heidelberg
contact email	h.nuskova@dkfz-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD021517

PRIDE project URI

• PRIDE
  1. PXD021517
     1. Label: PRIDE project
     2. Name: Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins