PXD021432

PXD021432 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Is infection the possible initiator of disc disease? An insight from proteomic analysis.
Description	There is raging controversy over the presence of bacteria in human lumbar discs in vivo, and if they represent contamination or infection. Proteomics can provide valuable insight by identifying proteins signifying bacterial presence and, also host defence response proteins (HDRPs), which will confirm infection. Hence this study was initiated mainly to address the controversy of infection as an aetiology for disc disorders through protein profiling.
HostingRepository	PRIDE
AnnounceDate	2025-01-08
AnnouncementXML	Submission_2025-01-07_16:29:05.463.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD021432
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Chitraa Tangavel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidoethyl-L-cysteine; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-11 03:00:51	ID requested
⏵ 1	2025-01-07 16:29:06	announced

Publication List

10.1007/s00586-017-4972-3;
Rajasekaran S, Tangavel C, Aiyer SN, Nayagam SM, Raveendran M, Demonte NL, Subbaiah P, Kanna R, Shetty AP, Dharmalingam K, ISSLS PRIZE IN CLINICAL SCIENCE 2017: Is infection the possible initiator of disc disease? An insight from proteomic analysis. Eur Spine J, 26(5):1384-1400(2017) [pubmed]
10.6019/PXD021432;

10.1007/s00586-017-4972-3;

Rajasekaran S, Tangavel C, Aiyer SN, Nayagam SM, Raveendran M, Demonte NL, Subbaiah P, Kanna R, Shetty AP, Dharmalingam K, ISSLS PRIZE IN CLINICAL SCIENCE 2017: Is infection the possible initiator of disc disease? An insight from proteomic analysis. Eur Spine J, 26(5):1384-1400(2017) [pubmed]

10.6019/PXD021432;

Keyword List

submitter keyword: Human IVD, NP tissues, Tandem mass spectrometry, Infective etiology

submitter keyword: Human IVD, NP tissues, Tandem mass spectrometry, Infective etiology

Contact List

Dr Chitraa Tangavel
contact affiliation	Research Scientist, Ganga Orthopedic Research and Education Foundation, 187, Mettupalayam Road, Kavundampalayam, Coimbatore- 641030, Tamil Nadu, India
contact email	cthangavel@gmail.com
lab head
Chitraa Tangavel
contact affiliation	Research Scientist, Ganga Orthopedic Research and Education Foundation, 187, Mettupalayam Road, Kavundampalayam, Coimbatore- 641030, Tamil Nadu, India
contact email	cthangavel@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD021432
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD021432

PRIDE project URI

Repository Record List

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