PXD021338 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation. |
Description | Protein composition of human ovarian follicular fluid (FF) constitutes the microenvironment for oocyte development. Several proteomics studies of FF from pre-ovulatory follicles have revealed insights on oocyte maturation, however, there is a lack of knowledge on changes produced at protein levels in the FF of human small antral follicles (hSAF) related to the upcoming oocyte maturation. Using mass spectrometry-based proteomics, we evaluated the protein composition of FF that surrounds oocytes capable to reach metaphase II (MII) after IVM with the protein profile of FF that surrounds immature oocytes. The samples were collected from small antral follicles (size 6.0 ± 1.5 mm) extracted from six women, from which two or three samples were extracted. The comparison was based on both, a multivariate (sPLS-DA) and univariate analyses (t-test). |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2021-09-09_09:12:12.355.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Indira Pla Parada |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-09-07 00:53:07 | ID requested | |
⏵ 1 | 2021-09-09 09:12:13 | announced | |
Publication List
Pla I, Sanchez A, Pors SE, Pawlowski K, Appelqvist R, Sahlin KB, Poulsen LC, Marko-Varga G, Andersen CY, Malm J, Proteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation. Hum Reprod, 36(3):756-770(2021) [pubmed] |
Keyword List
submitter keyword: follicular fluid, small antral follicles, proteomics, oocyte maturation. |
Contact List
Johan Malm |
contact affiliation | Clinical Chemistry, Department of Translational Medicine, Lund University, Skane University Hospital Malmö, 205 02 Malmö, Sweden. |
contact email | johan.malm@med.lu.se |
lab head | |
Indira Pla Parada |
contact affiliation | Lund university |
contact email | indira.pla_parada@med.lu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
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[ - ]
- PRIDE
- PXD021338
- Label: PRIDE project
- Name: Proteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation.