PXD021323

PXD021323 is an original dataset announced via ProteomeXchange.

Title	Deletion of miR-15a/16-1 in murine germinal center B-cells.
Description	Given the tumor suppressing function of miR-15a/16-1 cluster, we studied its role in the germinal center B-cells that give rise to most lymphoid malignancies.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_09:47:50.202.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tomasz Sewastianik
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-04 08:23:47	ID requested
⏵ 1	2021-09-09 09:47:50	announced

Sewastianik T, Straubhaar JR, Zhao JJ, Samur MK, Adler K, Tanton HE, Shanmugam V, Nadeem O, Dennis PS, Pillai V, Wang J, Jiang M, Lin J, Huang Y, Brooks D, Bouxsein M, Dorfman DM, Pinkus GS, Robbiani DF, Ghobrial IM, Budnik B, Jarolim P, Munshi NC, Anderson KC, Carrasco RD, miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms. Blood, 137(14):1905-1919(2021) [pubmed]

submitter keyword: Mouse, B-cell, germinal center, proteomics

Ruben D. Carrasco
contact affiliation	Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215
contact email	ruben_carrasco@dfci.harvard.edu
lab head
Tomasz Sewastianik
contact affiliation	Dana-Farber Cancer Institute, Boston, MA, USA Harvard Medical School, Boston, MA, USA
contact email	Tomasz_Sewastianik@dfci.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD021323

PRIDE project URI

• PRIDE
  1. PXD021323
     1. Label: PRIDE project
     2. Name: Deletion of miR-15a/16-1 in murine germinal center B-cells.