PXD021254

PXD021254 is an original dataset announced via ProteomeXchange.

Title	Quantitative phosphoproteomics of chronic sunitinib treated renal cell carcinoma 786-O cells with GPR30 agonist G-1
Description	In this project, we generated chronic sunitinib-treated 786-O cell, a renal cell carcinoma cell line. In order to investigate the possible effect of GPR30 agonist, G-1, on the growth-inhibtion related signaling pathways, we treated either parental both parental and chronic sunitinib-treated 786-O cells were treated either by vehicle-only (i.e. 0.1% DMSO) or 2 μM G-1 for 48 h. Therefore, there were three groups for comparison, including G-1 treatment (G-1 vs. parental), chronic sunitinib-treatment (SunR vs. parental), and G-1 treatment in SunR cells (SunR&G-1 vs. parental).
HostingRepository	PRIDE
AnnounceDate	2021-04-28
AnnouncementXML	Submission_2021-04-27_22:05:58.738.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei-Chi Ku
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap XL

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-01 04:33:24	ID requested
1	2021-04-27 21:06:41	announced
⏵ 2	2021-04-27 22:05:59	announced	2021-04-28: Updated project metadata.

Chen SK, Wang YC, Lin TY, Wu HJ, Huang CJ, Ku WC, G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma. Cancer Genomics Proteomics, 18(3):207-220(2021) [pubmed]

10.21873/CGP.20253;

submitter keyword: renal cell carcinoma, sunitinib, GPR30

Wei-Chi Ku
contact affiliation	School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
contact email	089052@mail.fju.edu.tw
lab head
Wei-Chi Ku
contact affiliation	Fu Jen Catholic University
contact email	089052@mail.fju.edu.tw
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD021254
     1. Label: PRIDE project
     2. Name: Quantitative phosphoproteomics of chronic sunitinib treated renal cell carcinoma 786-O cells with GPR30 agonist G-1