PXD021244 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Adult mouse choroid plexus OTX2 Co-IP |
Description | To analyze OTX2 function in adult choroid plexus, we performed several OTX2 co-immunoprecipitation (co-IP) experiments with mass spectrometry analysis to identify potential protein partners. We previously discovered that OTX2 protein also accumulates non-cell autonomously in subventricular zone (SVZ) and rostral migratory stream (RMS) astrocytes and in visual cortex (VCx) parvalbumin cells. The identification of alternate protein partners in cell-autonomous and non-cell-autonomous contexts would suggest OTX2 takes on specific roles after transferring between cells. In order to test this hypothesis, and to reinforce choroid plexus analysis, we also performed OTX2 co-IP on lysates from adult mouse SVZ, RMS and VCx. |
HostingRepository | PRIDE |
AnnounceDate | 2021-08-23 |
AnnouncementXML | Submission_2021-08-23_06:45:37.856.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Valentin SABATET |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-09-01 01:24:46 | ID requested | |
⏵ 1 | 2021-08-23 06:45:38 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mouse, choroid plexus, homeoprotein, OTX2 |
Contact List
Damarys Loew |
contact affiliation | Head of the Curie Institute Mass Spectrometry Platform |
contact email | damarys.loew@curie.fr |
lab head | |
Valentin SABATET |
contact affiliation | Curie Institute |
contact email | valentin.sabatet@curie.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD021244 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021244
- Label: PRIDE project
- Name: Adult mouse choroid plexus OTX2 Co-IP