PXD021236

PXD021236 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation-Mass Spectrometry Assays
Description	Here, we developed immunoprecipitation-mass spectrometry assays for the measurement of a low-abundance T1E4 TMPRSS2-ERG fusion protein, its isoforms and its interactome in VCaP prostate cancer cells.
HostingRepository	PRIDE
AnnounceDate	2021-03-29
AnnouncementXML	Submission_2021-03-29_02:57:47.702.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhiqiang Fu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-01 00:36:12	ID requested
⏵ 1	2021-03-29 02:57:48	announced

Publication List

Fu Z, Rais Y, Bismar TA, Hyndman ME, Le XC, Drabovich AP, Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation-Mass Spectrometry Assays. Mol Cell Proteomics, 20():100075(2021) [pubmed]

Fu Z, Rais Y, Bismar TA, Hyndman ME, Le XC, Drabovich AP, Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation-Mass Spectrometry Assays. Mol Cell Proteomics, 20():100075(2021) [pubmed]

Keyword List

submitter keyword: TMPRSS2-ERG fusion
VCaP cells
ERG protein isoforms
proteomics
mass spectrometry
selected reaction monitoring
ERG interactome
cBAF complex
canonical SWI/SNF complex

submitter keyword: TMPRSS2-ERG fusion

VCaP cells

ERG protein isoforms

proteomics

mass spectrometry

selected reaction monitoring

ERG interactome

cBAF complex

canonical SWI/SNF complex

Contact List

Andrei P. Drabovich
contact affiliation	Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
contact email	andrei.drabovich@ualberta.ca
lab head
Zhiqiang Fu
contact affiliation	University of Alberta
contact email	zfu6@ualberta.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD021236
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD021236

PRIDE project URI

Repository Record List

[ + ]