PXD021210

PXD021210 is an original dataset announced via ProteomeXchange.

Title	Quantitative TMT proteomics of brainstem in spontaneously hypertensive rats
Description	The brainstem, the core of the central nervous system, plays a vital role in controlling arterial blood pressure and its elevation of hypertension subtypes, especially essential hypertension. Integrative metabolic and proteomic profiling was performed on the brainstem samples of 11-week-old spontaneously hypertensive rats (SHRs) and age-matched normotensive Wistar rats, using hydrophilic interaction liquid chromatography-quadrupole/time-of-flight mass spectrometry (HILIC-Q/TOFMS) and nano-liquid chromatography-high-resolution-mass spectrometry (nano-LC-high-resolution-MS) combined with quantitative tandem mass tags (TMT).
HostingRepository	PRIDE
AnnounceDate	2020-09-24
AnnouncementXML	Submission_2020-09-24_00:52:33.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Cheng Yu
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-31 01:19:08	ID requested
⏵ 1	2020-09-24 00:52:34	announced

Cheng Y, Sun D, Zhu B, Zhou W, Lv C, Kou F, Wei H, Integrative Metabolic and Proteomic Profiling of the Brainstem in Spontaneously Hypertensive Rats. J Proteome Res, 19(10):4114-4124(2020) [pubmed]

submitter keyword: Brainstem, spontaneously hypertensive rats/SHR rats, quantitative proteome, TMT

Yu Cheng
contact affiliation	Institute of Interdisciplinary Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
contact email	ycheng_16@163.com
lab head
Cheng Yu
contact affiliation	Shanghai Jiao Tong University
contact email	ycheng_16@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD021210

PRIDE project URI

• PRIDE
  1. PXD021210
     1. Label: PRIDE project
     2. Name: Quantitative TMT proteomics of brainstem in spontaneously hypertensive rats