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PXD021176

PXD021176 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA TLR-inducible Cyclin J regulates inflammatory and anti-tumor responses by suppressing macrophage glycolysis via CDKs
DescriptionProteome and phosphoproteome analyses were performed to identify CDK substrates whose phosphorylation is induced by Cyclin J in macrophages. In the first experiment, RAW264.7 cells synchronized in G2/M phase by Nocodazole were treated with CDK inhibitors, Flavopiridol or Roscovitine, followed by phosphoproteomics. In the second experiment, proteome and phosphoproteome analyses were performed to characterize RAW264.7 cells inducibly expressing Cyclin J.
HostingRepositoryjPOST
AnnounceDate2021-08-28
AnnouncementXMLSubmission_2022-09-18_03:49:12.462.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuki Yoshikawa
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListL-methionine sulfoxide; S-carboxamidomethyl-L-cysteine; TMT6plex reporter+balance reagent N-acylated residue; TMT6plex reporter+balance reagent acylated N-terminal; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-27 20:59:07ID requested
12021-08-27 08:00:03announced
22022-09-18 03:49:12announced2022-09-18: Updated FTP location.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: RAW264.7, mouse, proteomics, phosphoproteomics, TMT
Contact List
Osamu Takeuchi
lab head
Yuki Yoshikawa
contact affiliationKyoto University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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