PXD021176

PXD021176 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A TLR-inducible Cyclin J regulates inflammatory and anti-tumor responses by suppressing macrophage glycolysis via CDKs
Description	Proteome and phosphoproteome analyses were performed to identify CDK substrates whose phosphorylation is induced by Cyclin J in macrophages. In the first experiment, RAW264.7 cells synchronized in G2/M phase by Nocodazole were treated with CDK inhibitors, Flavopiridol or Roscovitine, followed by phosphoproteomics. In the second experiment, proteome and phosphoproteome analyses were performed to characterize RAW264.7 cells inducibly expressing Cyclin J.
HostingRepository	jPOST
AnnounceDate	2021-08-28
AnnouncementXML	Submission_2022-09-18_03:49:12.462.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuki Yoshikawa
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	L-methionine sulfoxide; S-carboxamidomethyl-L-cysteine; TMT6plex reporter+balance reagent N-acylated residue; TMT6plex reporter+balance reagent acylated N-terminal; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-27 20:59:07	ID requested
1	2021-08-27 08:00:03	announced
⏵ 2	2022-09-18 03:49:12	announced	2022-09-18: Updated FTP location.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: RAW264.7, mouse, proteomics, phosphoproteomics, TMT

submitter keyword: RAW264.7, mouse, proteomics, phosphoproteomics, TMT

Contact List

Osamu Takeuchi
lab head
Yuki Yoshikawa
contact affiliation	Kyoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000949/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000949/