PXD021122

PXD021122 is an original dataset announced via ProteomeXchange.

Title	Isobaric tags for relative and absolute quantitation labeling coupled with 2D-LC MS/MS proteomics analysis of anterior insula in morphine induced place preference rats with high frequency deep brain stimulation intervention
Description	The rats were implanted bilaterally with electrodes in anterior insula and then trained to morphine conditioned place preference and chronic high frequency electrical stimulation was applied during the withdrawal phase. Proteomics analysis of the rat anterior insula was performed using isobaric tags for relative and absolute quantitation labeling (iTRAQ) coupled with 2D-LC MS/MS
HostingRepository	iProX
AnnounceDate	2020-08-25
AnnouncementXML	Submission_2023-03-01_23:08:02.893.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haigang Chang
SpeciesList	scientific name: Rattus rattus; NCBI TaxID: 10117;
ModificationList	iTRAQ8plex reporter+balance reagent acylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-25 19:36:11	ID requested
1	2020-09-13 22:54:14	announced
⏵ 2	2023-03-01 23:08:03	announced	2023-03-02: Update publication information.

Chang H, Gao C, Sun K, Xiao L, Li X, Jiang S, Zhu C, Sun T, Jin Z, Wang F, Continuous High Frequency Deep Brain Stimulation of the Rat Anterior Insula Attenuates the Relapse Post Withdrawal and Strengthens the Extinction of Morphine Seeking. Front Psychiatry, 11():577155(2020) [pubmed]

submitter keyword: rat, insula, morphine, deep brain stimulation, iTRAQ

Wang Feng
contact affiliation	Department of Neurosurgery, General Hospital of Ningxia Medical University
contact email	nxwwang@163.com
lab head
Haigang Chang
contact affiliation	Department of Neurosurgery, General Hospital of Ningxia Medical University
contact email	chg2007@163.com
dataset submitter

iProX dataset URI