PXD021109

PXD021109 is an original dataset announced via ProteomeXchange.

Title	Global Phosphoproteomics Pinpoints Uncharted Gcn2-Mediated Modes of Translational Control
Description	To identify new Gcn2 target proteins, we performed a set of Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based quantitative phosphoproteomics experiments, in which we compared WT cells to gcn2∆ and sui2S52A cells (n=3), all treated, or not, with rapamycin, which has previously been shown to stimulate eIF2alpha phosphorylation by Gcn2.
HostingRepository	PRIDE
AnnounceDate	2021-03-22
AnnouncementXML	Submission_2021-03-21_23:09:05.982.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-25 06:37:54	ID requested
⏵ 1	2021-03-21 23:09:06	announced

Dokl, á, dal L, Stumpe M, Pillet B, Hu Z, Garcia Osuna GM, Kressler D, Dengjel J, De Virgilio C, Global phosphoproteomics pinpoints uncharted Gcn2-mediated mechanisms of translational control. Mol Cell, 81(9):1879-1889.e6(2021) [pubmed]

submitter keyword: phosphoproteomics, yeast, LC-MS/MS, translation, rapamycin

Joern Dengjel
contact affiliation	Dr. Jörn Dengjel Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD021109

PRIDE project URI

• PRIDE
  1. PXD021109
     1. Label: PRIDE project
     2. Name: Global Phosphoproteomics Pinpoints Uncharted Gcn2-Mediated Modes of Translational Control