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PXD021023

PXD021023 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInvestigating byssogenesis with proteomic analysis of byssus, foot and mantle in Mytilus mussels by LC-MS/MS
DescriptionMussels synthesize an interesting class of biological materials with unique properties to adhere onto virtually any solid surface. Inter- and cross-species analyses have revealed that mussel byssus fabrication is influenced by environmental factors. In this study, proteins expressed specifically byssus and in the byssal-producing organ (foot) were examined for two mussel species from the Mytilidae family using liquid chromatography coupled with high-resolution tandem mass spectrometry (LC-MS/MS). The main goal was to describe which proteins are exclusively expressed in the mussel's foot gland, which is responsible for byssus secretion. Proteins uniquely found in the foot samples have been found by comparing to a control tissue (mantle). The overlap with proteins found in byssus samples were also investigated. A restricted list of these proteins have been highlighted as byssus-related, believed to contribute to the unique properties of byssus, such as securing adhesion and toughness, and plasticity based on environmental factors (including promoter regulation). This work may provide further directions on thread biofabrication and additional information on its regulation, as well as contribute to a more complete description of the mussel proteome.
HostingRepositoryPRIDE
AnnounceDate2020-09-17
AnnouncementXMLSubmission_2020-09-17_03:39:10.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD021023
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLekha Sleno
SpeciesList scientific name: Mytilus californianus; NCBI TaxID: 6549; scientific name: Mytilus edulis; NCBI TaxID: 6550;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-20 04:15:26ID requested
12020-09-17 03:39:11announced
Publication List
Sansoucy M, Tremblay R, Carrington E, Marcotte I, Sleno L, Investigating Byssogenesis with Proteomic Analysis of Byssus, Foot, and Mantle in Mytilus Mussels by LC-MS/MS. Proteomics, 21(2):e2000014(2021) [pubmed]
Keyword List
submitter keyword: Mussel, byssus, foot, LC-MS/MS, bottom-up proteomics
Contact List
Lekha Sleno
contact affiliationBioanalytical Mass Spectrometry Research Group, Chemistry Department, Université du Québec à Montréal (UQAM) Montréal (Québec) Canada (lab head)
contact emailsleno.lekha@uqam.ca
lab head
Lekha Sleno
contact affiliationUniversité du Québec à Montréal (UQÀM), Chemistry Department / Pharmaqam, Montréal, QC, Canada
contact emailsleno.lekha@uqam.ca
dataset submitter
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Dataset FTP location
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