PXD021023 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Investigating byssogenesis with proteomic analysis of byssus, foot and mantle in Mytilus mussels by LC-MS/MS |
Description | Mussels synthesize an interesting class of biological materials with unique properties to adhere onto virtually any solid surface. Inter- and cross-species analyses have revealed that mussel byssus fabrication is influenced by environmental factors. In this study, proteins expressed specifically byssus and in the byssal-producing organ (foot) were examined for two mussel species from the Mytilidae family using liquid chromatography coupled with high-resolution tandem mass spectrometry (LC-MS/MS). The main goal was to describe which proteins are exclusively expressed in the mussel's foot gland, which is responsible for byssus secretion. Proteins uniquely found in the foot samples have been found by comparing to a control tissue (mantle). The overlap with proteins found in byssus samples were also investigated. A restricted list of these proteins have been highlighted as byssus-related, believed to contribute to the unique properties of byssus, such as securing adhesion and toughness, and plasticity based on environmental factors (including promoter regulation). This work may provide further directions on thread biofabrication and additional information on its regulation, as well as contribute to a more complete description of the mussel proteome. |
HostingRepository | PRIDE |
AnnounceDate | 2020-09-17 |
AnnouncementXML | Submission_2020-09-17_03:39:10.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD021023 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Lekha Sleno |
SpeciesList | scientific name: Mytilus californianus; NCBI TaxID: 6549; scientific name: Mytilus edulis; NCBI TaxID: 6550; |
ModificationList | iodoacetamide derivatized residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-20 04:15:26 | ID requested | |
⏵ 1 | 2020-09-17 03:39:11 | announced | |
Publication List
Sansoucy M, Tremblay R, Carrington E, Marcotte I, Sleno L, Investigating Byssogenesis with Proteomic Analysis of Byssus, Foot, and Mantle in Mytilus Mussels by LC-MS/MS. Proteomics, 21(2):e2000014(2021) [pubmed] |
Keyword List
submitter keyword: Mussel, byssus, foot, LC-MS/MS, bottom-up proteomics |
Contact List
Lekha Sleno |
contact affiliation | Bioanalytical Mass Spectrometry Research Group, Chemistry Department, Université du Québec à Montréal (UQAM) Montréal (Québec) Canada (lab head) |
contact email | sleno.lekha@uqam.ca |
lab head | |
Lekha Sleno |
contact affiliation | Université du Québec à Montréal (UQÀM), Chemistry Department / Pharmaqam, Montréal, QC, Canada |
contact email | sleno.lekha@uqam.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021023
- Label: PRIDE project
- Name: Investigating byssogenesis with proteomic analysis of byssus, foot and mantle in Mytilus mussels by LC-MS/MS