PXD021012

PXD021012 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	DIA-MS based proteome analysis of HL-60 cells treated with new anti-cancer drug (TAS4464)
Description	We investigated the protein change of HL-60 cells with TAS4464 treatment in time series (0 h, 1h, 4h, 8h, 16h, 24h) by overlapping DIA-MS based proteome analysis. Spectral library was created by analyzing pooled samples by five gas-phase fractionated overlapping DIA-MS measurements.
HostingRepository	jPOST
AnnounceDate	2021-08-20
AnnouncementXML	Submission_2022-09-18_03:29:57.062.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yusuke Kawashima
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; unknown modification
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-19 23:24:08	ID requested
1	2021-08-19 08:00:04	announced
2	2022-04-20 01:01:12	announced	2022-04-20: Updated PubMed.
⏵ 3	2022-09-18 03:29:57	announced	2022-09-18: Updated FTP location.

Publication List

Ochiiwa H, Ailiken G, Yokoyama M, Yamagata K, Nagano H, Yoshimura C, Muraoka H, Ishida K, Haruma T, Nakayama A, Hashimoto N, Murata K, Nishimura M, Kawashima Y, Ohara O, Ohkubo S, Tanaka T, TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia. Oncogene, 40(7):1217-1230(2021) [pubmed]

Ochiiwa H, Ailiken G, Yokoyama M, Yamagata K, Nagano H, Yoshimura C, Muraoka H, Ishida K, Haruma T, Nakayama A, Hashimoto N, Murata K, Nishimura M, Kawashima Y, Ohara O, Ohkubo S, Tanaka T, TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia. Oncogene, 40(7):1217-1230(2021) [pubmed]

Keyword List

submitter keyword: NAE inhibitor, leukemia

submitter keyword: NAE inhibitor, leukemia

Contact List

Tomoaki Tanaka
lab head
Yusuke Kawashima
contact affiliation	Kazusa DNA Research Institute
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000944/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000944/