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PXD020963

PXD020963 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLipoprotein profiles of human serum and golden hamster plasma
DescriptionThe lipoproteins of human serum and golden hamster plasma were deeper profiled by label-free proteomics and the shared proteins in lipoprotein particles from humans and golden hamsters were highlighted. The dynamic shared protein compositions of VLDL, LDL, and HDL from golden hamster plasma under normal and hyperlipidemic states were confirmed and compared by parallel reaction monitoring (PRM)-based targeted proteomics. This study was aimed to determine the relationship between the protein heterogeneity and functions of the three lipoproteins under normal conditions and explore the functional implication of protein dynamic change during the hyperlipidemic state.
HostingRepositoryiProX
AnnounceDate2020-08-18
AnnouncementXMLSubmission_2020-08-17_20:06:59.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMiao Lin
SpeciesList scientific name: Mesocricetus auratus; NCBI TaxID: 10036; scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-17 20:02:59ID requested
12020-08-17 20:06:59announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: differential proteomics, lipoproteins, hyperlipidemia, VLDL, LDL, HDL
Contact List
Jin-Lan Zhang
contact affiliationInstitute of Materia Medica, Chinese Academy Medical Sciences & Peking Union Medical College
contact emailzhjl@imm.ac.cn
lab head
Miao Lin
contact affiliationInstitute of Materia Medica, Chinese Academy Medical Sciences & Peking Union Medical College
contact emailmiaolin94@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI